Genes, Giants, Monsters, and Men by Joseph P. Farrell
Author:Joseph P. Farrell [Farrell, Joseph P.]
Language: eng
Format: epub
Tags: Retail, Archaeology, Anthropology, Amazon.com, Gnostic Dementia, Fringe Science, Ancient Aliens
ISBN: 9781936239092
Amazon: B004UFTXV8
Goodreads: 11071897
Publisher: Feral House
Published: 2015-06-19T16:00:00+00:00
But the method was obviously cumbersome, for with such a technique, mapping the human genome “would take 100,000 years, which alone might explain why a lot of very smart people initially thought the Human Genome Project a very stupid idea.”248 Clearly some sort of engineering revolution was needed if the approach was to be less cumbersome and capable of more rapid sequencing.
Enter Tim Hunkapiller and his revolutionary idea.
In the technique developed by Sanger, “the DNA letters were read by the researcher’s eyeball, scanning both across and up the gel at the same time, a process that was both error-prone and squintingly slow.”249 What was needed was a process that would mechanize the entire method. Tim’s idea was to color-code the last letters in each fragment by chemically attaching a different-colored dye to each of the four doctored, killjoy nucleotides: blue for C, yellow for G, red for T, and green for A. As each fragment in turn arrived at the bottom of the gel, the color of its last letter could be read by a detector, which would feed this information to a computer. If the process worked, several samples could be run at once.... Theoretically, it could sequence more DNA in a day than a single researcher could do in a year.250
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